BioTech

• Five small-molecule leads (ATX1-5) inhibit the activation of sortase A dimer and the subsequent bacterial invasion of mammalian cells - early stage treatment.
• Protein (ATPC) and peptide (ATPN1) antagonize the bacterial invasion of mammalian cells by blocking the signals activating Sortase A enzyme - pre-early stage treatment.

TechBio

• Wave 2 Machine Vision accurately predicted the ATPC and ATPN1.
• Wave 3 Generative AI designed optimized second generation ATX-B1 compound.